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NOP2/Sun Domain Family, Member 2 (NSUN2) Peptide

NSUN2 Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN938320
  • Target See all NSUN2 products
    NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    FINSRIITVS MEDVKILLTQ ENPFFRKLSS ETYSQAKDLA KGSIVLKYEP
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of NSUN2 antibody,
    Alternative Names: NSUN2 control peptide, NSUN2 antibody Blocking Peptide, Anti-NSUN2 Blocking Peptide, Nol1/Nop2/Sun Domain Family Member 2 Blocking Peptide, FLJ20303 Blocking Peptide, MISU Blocking Peptide, SAKI Blocking Peptide, TRM4 Blocking Peptide, NSUN2, NSUN-2, NSUN 2, NSUN-2 Blocking Peptide, NSUN 2 Blocking Peptide
    Purification
    Immunoaffinity chromatography
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))
    Synonyms
    D13Wsu123e Peptide, Misu Peptide, MISU Peptide, MRT5 Peptide, SAKI Peptide, TRM4 Peptide, RGD1311954 Peptide, NOL1/NOP2/Sun domain family member 2 Peptide, NOP2/Sun RNA methyltransferase family member 2 Peptide, NOP2/Sun RNA methyltransferase family, member 2 Peptide, NOP2/Sun RNA methyltransferase family member 2 S homeolog Peptide, Nsun2 Peptide, NSUN2 Peptide, nsun2.S Peptide
    Background
    Maturation of cytoplasmic tRNAs includes splicing of introns, which are located 1 nucleotide 3-prime from the anticodon in all intron-containing tRNA genes. In tRNA-leu(CAA), the first position of the anticodon, C34, is converted to 5-methylcytosine, a modification necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. NSUN2 is a methyltransferase that catalyzes the intron-dependent formation of 5-methylcytosine at C34 of tRNA-leu(CAA).
    Molecular Weight
    86 kDa
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