Myelin Basic Protein (MBP) Peptide
-
- Target See all MBP products
- MBP (Myelin Basic Protein (MBP))
- Peptide Type
- Synthetic
- Origin
- Mammalian
-
Source
- Synthetic
- Application
- Western Blotting (WB), Blocking Peptide (BP), Immunohistochemistry (IHC)
- Sequence
- FGGDRGAPKR GSGKDSHHPA RTAHYGSLPQ KSHGRTQDEN PVVHFFKNIV
- Characteristics
-
A synthetic peptide for use as a blocking control in assays to test for specificity of MBP antibody,
Alternative Names: MBP control peptide, MBP antibody Blocking Peptide, Anti-MBP Blocking Peptide, Myelin Basic Protein Blocking Peptide, MGC99675 Blocking Peptide
-
-
- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
-
- Target
- MBP (Myelin Basic Protein (MBP))
- Background
- The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells.
- Molecular Weight
- 33 kDa
-