Growth Arrest and DNA-Damage-Inducible, beta (GADD45B) Peptide
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- Target See all GADD45B products
- GADD45B (Growth Arrest and DNA-Damage-Inducible, beta (GADD45B))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- FCCDNDINIV RVSGMQRLAQ LLGEPAETQG TTEARDLHCL LVTNPHTDAW
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of GADD45 B antibody,
Alternative Names: GADD45B control peptide, GADD45B antibody Blocking Peptide, Anti-GADD45B Blocking Peptide, Growth Arrest And Dna-Damage-Inducible Beta Blocking Peptide, DKFZP566B133 Blocking Peptide, GADD45BETA Blocking Peptide, MYD118 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- GADD45B (Growth Arrest and DNA-Damage-Inducible, beta (GADD45B))
- Synonyms
- GADD45BETA Peptide, MYD118 Peptide, AI323528 Peptide, Myd118 Peptide, CS131 Peptide, cb196 Peptide, gadd45b Peptide, gadd45b2 Peptide, sb:cb196 Peptide, zgc:73104 Peptide, gadd45beta Peptide, wu:fa92d10 Peptide, wu:fa98h12 Peptide, wu:fk65h03 Peptide, zgc:111973 Peptide, gadd45b1 Peptide, gadd45bl Peptide, zgc:112453 Peptide, growth arrest and DNA damage inducible beta Peptide, growth arrest and DNA-damage-inducible 45 beta Peptide, growth arrest and DNA-damage-inducible, beta Peptide, growth arrest and DNA-damage-inducible, beta a Peptide, growth arrest and DNA-damage-inducible, beta b Peptide, GADD45B Peptide, Gadd45b Peptide, gadd45ba Peptide, gadd45bb Peptide
- Background
- GADD45B is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth.
- Molecular Weight
- 18 kDa
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