MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) Peptide
MRE11A
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all Mre11 (MRE11A) products
- Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- DTFVTLDEIL RLAQENEVDF ILLGGDLFHE NKPSRKTLHT CLELLRKYCM
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of MRE11 A antibody,
Alternative Names: MRE11A control peptide, MRE11A antibody Blocking Peptide, Anti-MRE11A Blocking Peptide, MRE11 meiotic recombination 11 homolog A, S. cerevisiae Blocking Peptide, ATLD Blocking Peptide, HNGS1 Blocking Peptide, MRE11 Blocking Peptide, MRE11B Blocking Peptide, MRE11A, MREA-11, MREA 11, MREA-11 Blocking Peptide, MREA 11 Blocking Peptide - Purification
- The antibody is affinity purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
- Background
- This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog, this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
- Molecular Weight
- 80 kDa
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