Runt-Related Transcription Factor 2 (RUNX2) Peptide
RUNX2
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all RUNX2 products
- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- DTATSDFCLW PSTLSKKSQA GASELGPFSD PRQFPSISSL TESRFSNPRM
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of RUNX2 antibody,
Alternative Names: RUNX2 control peptide, RUNX2 antibody Blocking Peptide, Anti-RUNX2 Blocking Peptide, Runt-Related Transcription Factor 2 Blocking Peptide, RUNX2, RUNX-2, RUNX 2, RUNX-2 Blocking Peptide, RUNX 2 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
- Synonyms
- AML3 Peptide, CBF-alpha-1 Peptide, CBFA1 Peptide, CCD Peptide, CCD1 Peptide, CLCD Peptide, OSF-2 Peptide, OSF2 Peptide, PEA2aA Peptide, PEBP2aA Peptide, Cbf Peptide, Cbfa-1 Peptide, Cbfa1 Peptide, LS3 Peptide, Osf2 Peptide, Pebp2a1 Peptide, Pebpa2a Peptide, runx2 Peptide, RUNX2 Peptide, ccd Peptide, aml3 Peptide, ccd1 Peptide, osf2 Peptide, cbfa1 Peptide, pea2aa Peptide, pebp2a1 Peptide, pebp2a2 Peptide, pebp2aa Peptide, pebp2aa1 Peptide, runt related transcription factor 2 Peptide, runt-related transcription factor 2a Peptide, runt-related transcription factor 2 Peptide, runt related transcription factor 2 L homeolog Peptide, RUNX2 Peptide, runx2a Peptide, Runx2 Peptide, runx2 Peptide, LOC703331 Peptide, LOC100549663 Peptide, runx2.L Peptide
- Background
- RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis, acting as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants, encoding different protein isoforms, result from alternate promoter use as well as alternate splicing.
- Molecular Weight
- 57 kDa
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