Interleukin 1, beta (IL1B) Peptide
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- Target See all IL-1 beta (IL1B) products
- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- DLDLCPLDGG IQLRISDHHY SKGFRQAASV VVAMDKLRKM LVPCPQTFQE
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of IL1 B antibody,
Alternative Names: IL1 beta control peptide, IL1 beta antibody Blocking Peptide, Anti-IL1 beta Blocking Peptide, Interleukin 1 Beta Blocking Peptide, IL-1 Blocking Peptide, IL1-BETA Blocking Peptide, IL1F2 Blocking Peptide, IL1B Blocking Peptide, IL1 beta, IL beta-1, IL beta 1, IL beta-1 Blocking Peptide, IL beta 1 Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
- Synonyms
- IL-1 Peptide, IL1-BETA Peptide, IL1F2 Peptide, IL-1BETA Peptide, IL1beta Peptide, il1-b Peptide, zgc:111873 Peptide, IL-1B Peptide, IL-1beta Peptide, Il-1b Peptide, IL1B Peptide, IL-1 beta Peptide, IL-1b Peptide, interleukin 1 beta Peptide, interleukin 1, beta Peptide, IL1B Peptide, il1b Peptide, Il1b Peptide
- Background
- IL1B is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. The gene encoding IL1B and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
- Molecular Weight
- 17 kDa
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