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Interleukin 1, beta (IL1B) Peptide

IL1B Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN937423
  • Target See all IL-1 beta (IL1B) products
    IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 11
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    DLDLCPLDGG IQLRISDHHY SKGFRQAASV VVAMDKLRKM LVPCPQTFQE
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of IL1 B antibody,
    Alternative Names: IL1 beta control peptide, IL1 beta antibody Blocking Peptide, Anti-IL1 beta Blocking Peptide, Interleukin 1 Beta Blocking Peptide, IL-1 Blocking Peptide, IL1-BETA Blocking Peptide, IL1F2 Blocking Peptide, IL1B Blocking Peptide, IL1 beta, IL beta-1, IL beta 1, IL beta-1 Blocking Peptide, IL beta 1 Blocking Peptide
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
    Synonyms
    IL-1 Peptide, IL1-BETA Peptide, IL1F2 Peptide, IL-1BETA Peptide, IL1beta Peptide, il1-b Peptide, zgc:111873 Peptide, IL-1B Peptide, IL-1beta Peptide, Il-1b Peptide, IL1B Peptide, IL-1 beta Peptide, IL-1b Peptide, interleukin 1 beta Peptide, interleukin 1, beta Peptide, IL1B Peptide, il1b Peptide, Il1b Peptide
    Background
    IL1B is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. The gene encoding IL1B and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
    Molecular Weight
    17 kDa
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