Titin-Cap (Telethonin) (TCAP) Peptide
TCAP
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN937196
Quick Overview for Titin-Cap (Telethonin) (TCAP) Peptide (ABIN937196)
Target
TCAP
(Titin-Cap (Telethonin) (TCAP))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- CSLHEEDTQR HETYHQQGQC QVLVQRSPWL MMRMGILGRG LQEYQLPYQR
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of TCAP antibody,
Alternative Names: TCAP control peptide, TCAP antibody Blocking Peptide, Anti-TCAP Blocking Peptide, Titin-Cap Blocking Peptide, Telethonin Blocking Peptide, CMD1N Blocking Peptide, LGMD2G Blocking Peptide, T-cap Blocking Peptide, TELE Blocking Peptide, telethonin Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- TCAP (Titin-Cap (Telethonin) (TCAP))
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Background
- Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. TCAP is a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in TCAP gene are associated with limb-girdle muscular dystrophy type 2G.
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Molecular Weight
- 19 kDa
Target
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