Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2) Peptide
PARK2
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all Parkin (PARK2) products
- Parkin (PARK2) (Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- YTRYQQYGAE ECVLQMGGVL CPRPGCGAGL LPEQGQRKVT CEGGNGLGCG
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of Park2 antibody,
Alternative Names: Park2 control peptide, Park2 antibody Blocking Peptide, Anti-Park2 Blocking Peptide, Parkinson disease, autosomal recessive, juvenile 2, parkin Blocking Peptide, MGC130518 Blocking Peptide, PRKN Blocking Peptide, Park2, Park-2, Park 2, Park-2 Blocking Peptide, Park 2 Blocking Peptide - Purification
- Serum
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- Parkin (PARK2) (Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))
- Synonyms
- CG10523 Peptide, Dmel\\CG10523 Peptide, Dpark Peptide, SD01679 Peptide, dpk Peptide, AR-JP Peptide, LPRS2 Peptide, PDJ Peptide, PRKN Peptide, Park Peptide, Prkn Peptide, si:ch211-123f21.1 Peptide, zgc:112390 Peptide, pdr-1 Peptide, PARK2 Peptide, parkin Peptide, parkin RBR E3 ubiquitin protein ligase Peptide, Parkinson disease (autosomal recessive, juvenile) 2, parkin Peptide, park Peptide, PRKN Peptide, Prkn Peptide, prkn Peptide, CpipJ_CPIJ014867 Peptide, Park2 Peptide
- Background
- Park2 functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. These substrates include SYT11, CCNE1, GPR37, STUB1, a 22 kDa O-linked glycosylated isoform of SNCAIP, SEPT5 and AIMP2. Park2 may play a more general role in the ubiquitin proteasomal pathway by participating in the removal and/or detoxification of abnormally folded or damaged protein. Park2 limits the production of reactive oxygen species (ROS).
- Molecular Weight
- 51 kDa
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