Interleukin 1, beta (IL1B) (AA 117-269) Peptide
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- Target See all IL-1 beta (IL1B) products
- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
- Peptide Type
- Recombinant
- Protein Region
- AA 117-269
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Sequence
- MAPVRSLNCT LRDSQQKSLV MSGPYELKAL HLQGQDMEQQ VVFSMSFVQG EESNDKIPVA LGLKEKNLYL SCVLKDDKPT LQLESVDPKN YPKKKMEKRF VFNKIEINNK LEFESAQFPN WYISTSQAEN MPVFLGGTKG GQDITDFTMQ FVSS
- Characteristics
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Purified recombinant Human IL1 beta protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher. - Purity
- > 95 % pure
- Endotoxin Level
- < 1.0 EU per µg of protein (determined by LAL method)
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- Application Notes
- IL1 beta protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Supplied as a liquid in PBS, pH 7.4.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
- Storage Comment
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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Potential role of size and hemodynamics in the efficacy of vascular-targeted spherical drug carriers." in: Biomaterials, Vol. 31, Issue 6, pp. 1392-402, (2010) (PubMed).
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Potential role of size and hemodynamics in the efficacy of vascular-targeted spherical drug carriers." in: Biomaterials, Vol. 31, Issue 6, pp. 1392-402, (2010) (PubMed).
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- Target
- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
- Synonyms
- IL-1 Peptide, IL1-BETA Peptide, IL1F2 Peptide, IL-1BETA Peptide, IL1beta Peptide, il1-b Peptide, zgc:111873 Peptide, IL-1B Peptide, IL-1beta Peptide, Il-1b Peptide, IL1B Peptide, IL-1 beta Peptide, IL-1b Peptide, interleukin 1 beta Peptide, interleukin 1, beta Peptide, IL1B Peptide, il1b Peptide, Il1b Peptide
- Background
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Interleukin-1 (IL-1) has been considered a potentially important inflammatory mediator. It is composed of two distinct proteins, called as IL-1 alpha and IL-1 beta. IL-1 beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1 alpha and IL-1 beta bind to the same receptor and they are structurally related polypeptides that share approximately 20 % amino acid. Recombinant human IL-1 beta was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: IL beta 1 protein, IL1-beta protein, IL1B protein, Interleukin 1b protein, IL beta 1, IL-1B, Interleukin 1beta protein, IL1F2 protein, beta proprotein protein, IL-1 protein, IL beta-1, IL1 beta, interleukin 1 beta protein, Interleukin 1 protein, IL beta-1 protein - Molecular Weight
- 17 kDa (154 AA)
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