Mastermind-Like 1 (MAML1) (Middle Region) Peptide
-
- Target See all MAML1 products
- MAML1 (Mastermind-Like 1 (MAML1))
- Protein Region
- Middle Region
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- KPASPSSYKQ DFTNSKLLMM PSVNKSSPRP GGPYLQPSHV NLLSHQPPSN
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- MAML1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- MAML1 (Mastermind-Like 1 (MAML1))
- Synonyms
- mam1 Peptide, mam-1 Peptide, xmam1 Peptide, MAML1 Peptide, AI644666 Peptide, AW743257 Peptide, D930008C07Rik Peptide, Mam-1 Peptide, Mam1 Peptide, mKIAA0200 Peptide, mastermind like transcriptional coactivator 1 L homeolog Peptide, mastermind like transcriptional coactivator 1 Peptide, mastermind like 1 (Drosophila) Peptide, mastermind-like transcriptional coactivator 1 Peptide, maml1.L Peptide, MAML1 Peptide, Maml1 Peptide
- Background
-
This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway.
Alias Symbols: Mam1, Mam-1
Protein Size: 1016 - Gene ID
- 9794
- NCBI Accession
- NM_014757, NP_055572
- UniProt
- Q92585
-