Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) (Middle Region) Peptide
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- Target See all USP7 products
- USP7 (Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- QFFKSQGYRD GPGNPLRHNY EGTLRDLLQF FKPRQPKKLY YQQLKMKITD
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- USP7 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- USP7 (Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7))
- Synonyms
- CG1490 Peptide, Dmel\\CG1490 Peptide, USP7 Peptide, 2210010O09Rik Peptide, AA409944 Peptide, AA617399 Peptide, AU019296 Peptide, AW548146 Peptide, C80752 Peptide, Hausp Peptide, HAUSP Peptide, TEF1 Peptide, UBP Peptide, Ubiquitin-specific protease 7 Peptide, ubiquitin carboxyl-terminal hydrolase 7 Peptide, ubiquitin specific peptidase 7 Peptide, Usp7 Peptide, LOC100201254 Peptide, USP7 Peptide
- Background
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The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder.
Alias Symbols: TEF1, HAUSP
Protein Size: 1102 - Gene ID
- 7874
- NCBI Accession
- NM_003470, NP_001308787
- UniProt
- Q93009
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