Estrogen Receptor 1 (ESR1) (Middle Region) Peptide
ESR1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Estrogen Receptor alpha (ESR1) products
- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- RRGGRMLKHK RQRDDGEGRG EVGSAGDMRA ANLWPSPLMI KRSKKNSLAL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- ESR1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
- Synonyms
- LOC398734 Peptide, AA420328 Peptide, AU041214 Peptide, ER-alpha Peptide, ER[a] Peptide, ERa Peptide, ERalpha Peptide, ESR Peptide, Estr Peptide, Estra Peptide, Nr3a1 Peptide, NR3A1 Peptide, eralpha Peptide, zfER[a] Peptide, ER Peptide, ESRA Peptide, ESTRR Peptide, Era Peptide, akap12 Peptide, cb27 Peptide, esr1 Peptide, fb72g12 Peptide, id:ibd1202 Peptide, sb:cb27 Peptide, si:ch73-192g21.1 Peptide, wu:fb72g12 Peptide, wu:fc21c03 Peptide, Esr Peptide, RNESTROR Peptide, ERALPHA Peptide, er Peptide, esr Peptide, nr3a1 Peptide, XER Peptide, era Peptide, esra Peptide, ERbeta Peptide, xesr-1 Peptide, xlERalpha1 Peptide, xlERalpha2 Peptide, ESR1 Peptide, estrogen receptor 1 L homeolog Peptide, estrogen receptor 1 (alpha) Peptide, estrogen receptor 1 Peptide, A kinase (PRKA) anchor protein 12b Peptide, esr1.L Peptide, Esr1 Peptide, ESR1 Peptide, esr1 Peptide, akap12b Peptide
- Background
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This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.
Alias Symbols: ER, ESR, Era, ESRA, ESTRR, NR3A1
Protein Size: 312 - Gene ID
- 2099
- NCBI Accession
- NM_000125, NP_000116
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