Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B) (Middle Region) Peptide
EIF3B
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all EIF3B products
- EIF3B (Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- ENGDADEPSF SDPEDFVDDV SEEELLGDVL KDRPQEADGI DSVIVVDNVP
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- EIF3B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- EIF3B (Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B))
- Synonyms
- EIF3-ETA Peptide, EIF3-P110 Peptide, EIF3-P116 Peptide, EIF3S9 Peptide, PRT1 Peptide, AL033316 Peptide, AL033334 Peptide, AL033369 Peptide, AW208965 Peptide, D5Wsu45e Peptide, Eif3s9 Peptide, eif3-eta Peptide, eif3-p110 Peptide, eif3-p116 Peptide, eif3s9 Peptide, prt1 Peptide, ATEIF3B-2 Peptide, EIF3B Peptide, EUKARYOTIC TRANSLATION INITIATION FACTOR 3B Peptide, F18A17.30 Peptide, F18A17_30 Peptide, eukaryotic translation initiation factor 3B-2 Peptide, DDBDRAFT_0218512 Peptide, DDBDRAFT_0233929 Peptide, DDB_0218512 Peptide, DDB_0233929 Peptide, eIF-3-eta Peptide, eif3b Peptide, wu:fc17c01 Peptide, GB10123 Peptide, eIF3b Peptide, AO090005000892 Peptide, CaO19.6584 Peptide, eIF3 p90 Peptide, eukaryotic translation initiation factor 3 subunit B Peptide, eukaryotic translation initiation factor 3, subunit B Peptide, eukaryotic translation initiation factor 3B-2 Peptide, eukaryotic initiation factor Peptide, RNA recognition motif-containing protein RRM Peptide, eukaryotic translation initiation factor 3b Peptide, eukaryotic translation initiation factor 3 subunit B L homeolog Peptide, eukaryotic translation initiation factor 3, subunit Ba Peptide, eukaryotic translation initiation factor 3 subunit 9 Peptide, translation initiation factor eIF-3 subunit 9 Peptide, Eukaryotic translation initiation factor 3 subunit B Peptide, translation initiation factor eIF3 subunit b Peptide, EIF3B Peptide, Eif3b Peptide, eif3b Peptide, EIF3B-2 Peptide, eIF3s9 Peptide, eif3B Peptide, eif3b.L Peptide, eif3ba Peptide, LOC410100 Peptide, eIF3-S9 Peptide, AOR_1_1564174 Peptide, VDBG_02490 Peptide, PGTG_13070 Peptide, Tsp_02250 Peptide, eif-3.B Peptide, PRT1 Peptide
- Background
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RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.(Microbial infection) In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2.
Alias Symbols: PRT1, EIF3S9, EIF3-ETA, EIF3-P110, EIF3-P116
Protein Size: 873 - Gene ID
- 8662
- NCBI Accession
- NM_001037283, NP_001032360
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