Ubiquitin B (UBB) (C-Term) Peptide
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- Target See all Ubiquitin B (UBB) products
- Ubiquitin B (UBB)
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LIFAGKQLED GRTLSDYNIQ KESTLHLVLR LRGGMQIFVK TLTGKTITLE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- UBB Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Ubiquitin B (UBB)
- Synonyms
- AL033289 Peptide, Rps27a Peptide, Uba52 Peptide, Ubb2 Peptide, Ubc Peptide, UBC Peptide, Ubiquitin Peptide, UBB Peptide, Ubi-p63E Peptide, im:6892314 Peptide, si:ch211-202a12.3 Peptide, ubc Peptide, zUBC Peptide, zgc:172187 Peptide, ubiquitin B Peptide, ubiquitin C Peptide, UBB Peptide, Ubb Peptide, UBC Peptide, ubb Peptide
- Background
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This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants.
Alias Symbols: HEL-S-50
Protein Size: 229 - Gene ID
- 7314
- NCBI Accession
- NM_001281716, NP_001268645
- UniProt
- P0CG47
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