Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU) (Middle Region) Peptide
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- Target See all ISCU products
- ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Western Blotting (WB)
- Sequence
- SAPARLYHKK VVDHYENPRN VGSLDKTSKN VGTGLVGAPA CGDVMKLQIQ
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ISCU (Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (ISCU))
- Synonyms
- nifun Peptide, zC191D15.3 Peptide, si:ch211-191d15.3 Peptide, 2310020H20Rik Peptide, HML Peptide, ISU2 Peptide, NIFU Peptide, NIFUN Peptide, hnifU Peptide, RGD1309562 Peptide, AA407971 Peptide, Nifu Peptide, Nifun Peptide, iron-sulfur cluster assembly enzyme ISCU, mitochondrial Peptide, iron-sulfur cluster assembly enzyme Peptide, iron-sulfur cluster assembly enzyme a Peptide, LOC409130 Peptide, ISCU Peptide, iscua Peptide, Iscu Peptide
- Background
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Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria. A pseudogene of this gene is present on chromosome 1. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: HML, ISU2, NIFU, NIFUN, hnifU, 2310020H20Rik
Protein Size: 167 - Gene ID
- 23479
- NCBI Accession
- NM_014301, NP_055116
- UniProt
- Q9H1K1
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