ARP8 Actin-Related Protein 8 Homolog (ACTR8) (Middle Region) Peptide
ACTR8
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ACTR8 products
- ACTR8 (ARP8 Actin-Related Protein 8 Homolog (ACTR8))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- TLQHRSQGDP EDPHDEHYLL ATQSKQEQSA KATADRKSAS KPIGFEGDLR
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- ACTR8 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ACTR8 (ARP8 Actin-Related Protein 8 Homolog (ACTR8))
- Synonyms
- CG7846 Peptide, Dmel\\CG7846 Peptide, dArp8 Peptide, AT5G56185 Peptide, ATARP8 Peptide, MDA7.26 Peptide, actin-related protein 8 Peptide, actr8 Peptide, 5730542K05Rik Peptide, ARP8 Peptide, INO80N Peptide, hArp8 Peptide, wu:fe37a08 Peptide, wu:fi27e09 Peptide, zgc:55313 Peptide, Actin-related protein 8 Peptide, actin-related protein 8 Peptide, ARP8 actin related protein 8 homolog Peptide, ARP8 actin-related protein 8 Peptide, Arp8 Peptide, ARP8 Peptide, actr8 Peptide, Actr8 Peptide, ACTR8 Peptide
- Background
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Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA reoplication and probably DNA repair. Required for the recruitment of INO80 (and probably the INO80 complex) to sites of DNA damage. Strongly prefer nucleosomes and H3-H4 tetramers over H2A-H2B dimers, suggesting it may act as a nucleosome recognition module within the complex.
Alias Symbols: ARP8, hArp8, INO80N
Protein Size: 513 - Gene ID
- 93973
- NCBI Accession
- NM_022899, NP_075050
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