Ubiquitin Specific Peptidase 6 (USP6) (C-Term) Peptide
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- Target See all USP6 products
- USP6 (Ubiquitin Specific Peptidase 6 (USP6))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- DHEVALANGF LYEHEACGNG CGDGYSNGQL GNHSEEDSTD DQREDTHIKP
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- USP6 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- USP6 (Ubiquitin Specific Peptidase 6 (USP6))
- Synonyms
- HRP1 Peptide, TRE2 Peptide, TRE17 Peptide, Tre-2 Peptide, USP6-short Peptide, ubiquitin specific peptidase 6 Peptide, ubiquitin carboxyl-terminal hydrolase 6 Peptide, Ubiquitin carboxyl-terminal hydrolase 6, putative Peptide, USP6 Peptide, CNG04540 Peptide, ANI_1_2152104 Peptide, AOR_1_208094 Peptide, MCYG_00569 Peptide, CC1G_15273 Peptide, MGYG_01395 Peptide, CGB_G0160W Peptide, LOC100282385 Peptide
- Background
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Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.
Alias Symbols: HRP1, TRE2, TRE17, Tre-2, TRESMCR, USP6-short
Protein Size: 1406 - Gene ID
- 9098
- NCBI Accession
- NM_001304284, NP_001291213
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