NOP2/Sun Domain Family, Member 2 (NSUN2) (N-Term) Peptide
NSUN2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all NSUN2 products
- NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LEKFHQFLVS ETESGNISRQ EAVSMIPPLL LNVRPHHKIL DMCAAPGSKT
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-NSUN2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))
- Synonyms
- D13Wsu123e Peptide, Misu Peptide, MISU Peptide, MRT5 Peptide, SAKI Peptide, TRM4 Peptide, RGD1311954 Peptide, NOL1/NOP2/Sun domain family member 2 Peptide, NOP2/Sun RNA methyltransferase family member 2 Peptide, NOP2/Sun RNA methyltransferase family, member 2 Peptide, NOP2/Sun RNA methyltransferase family member 2 S homeolog Peptide, Nsun2 Peptide, NSUN2 Peptide, nsun2.S Peptide
- Background
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NSUN2 is a RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. NSUN2 methylates cytosine to 5- methylcytosine (m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) precursors, and at positions 48, 49 and 50 of tRNA(Gly)(GCC) precursors. It may act downstream of Myc to regulate epidermal cell growth and proliferation. And it is required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.
Alias Symbols: NSUN2,SAKI, TRM4,
Protein Size: 767 - Gene ID
- 54888
- NCBI Accession
- NP_060225
- UniProt
- Q08J23
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