conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (Middle Region) Peptide
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- Target See all IKK alpha (CHUK) products
- IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- GRRQGDLMES LEQRAIDLYK QLKHRPSDHS YSDSTEMVKI IVHTVQSQDR
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- CHUK Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- IKK alpha (CHUK) (conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK))
- Synonyms
- ikk Peptide, ikk1 Peptide, ikka Peptide, ikkalpha Peptide, CHUK Peptide, IKBKA Peptide, IKK-alpha Peptide, IKK1 Peptide, IKKA Peptide, NFKBIKA Peptide, TCF16 Peptide, AI256658 Peptide, Chuk1 Peptide, Fbx24 Peptide, Fbxo24 Peptide, Ikka Peptide, zgc:56539 Peptide, conserved helix-loop-helix ubiquitous kinase S homeolog Peptide, conserved helix-loop-helix ubiquitous kinase Peptide, chuk.S Peptide, CHUK Peptide, Chuk Peptide, chuk Peptide
- Background
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This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.
Alias Symbols: IKK1, IKKA, IKBKA, TCF16, NFKBIKA, IKK-alpha
Protein Size: 745 - Gene ID
- 1147
- NCBI Accession
- NM_001278, NP_001269
- UniProt
- O15111
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