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Glucokinase (Hexokinase 4) Regulator (GCKR) (N-Term) Peptide

GCKR Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5513028
  • Target See all GCKR products
    GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    VIETPEPGKW ELSGYEAAVP ITEKSNPLTQ DLDKADAENI VRLLGQCDAE
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-GCKR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))
    Background
    This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).

    Alias Symbols: GCKR,

    Protein Size: 625
    Gene ID
    2646
    NCBI Accession
    NP_001477
    UniProt
    Q14397
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