Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB) (Middle Region) Peptide
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- Target See all SDHB products
- SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- AQTAAATAPR IKKFAIYRWD PDKAGDKPHM QTYEVDLNKC GPMVLDALIK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-SDHB Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SDHB (Succinate Dehydrogenase Complex, Subunit B, Iron Sulfur (Ip) (SDHB))
- Synonyms
- succinate dehydrogenase 2-3 Peptide, CG3283 Peptide, Dmel\\CG3283 Peptide, Ip Peptide, SDH Peptide, SDH-IP Peptide, SDH-Ip Peptide, SDHb Peptide, sdhB Peptide, CWS2 Peptide, IP Peptide, PGL4 Peptide, SDH1 Peptide, SDH2 Peptide, SDHIP Peptide, 0710008N11Rik Peptide, fj46d06 Peptide, wu:fj46d06 Peptide, succinate dehydrogenase complex iron sulfur subunit B Peptide, succinate dehydrogenase [ubiquinone] iron-sulfur subunit 3 Peptide, Succinate dehydrogenase, subunit B (iron-sulfur) Peptide, succinate dehydrogenase complex subunit B, iron sulfur (Ip) Peptide, succinate dehydrogenase complex, subunit B, iron sulfur (Ip) Peptide, succinate dehydrogenase complex subunit B, iron sulfur (Ip) S homeolog Peptide, SDHB Peptide, SDH2-3 Peptide, SdhB Peptide, sdhb Peptide, Sdhb Peptide, sdhb.S Peptide
- Background
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Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
Alias Symbols: IP, SDH, CWS2, PGL4, SDH1, SDH2, SDHIP
Protein Size: 280 - Gene ID
- 6390
- NCBI Accession
- NM_003000, NP_002991
- UniProt
- P21912
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