Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 1 (APPL1) (Middle Region) Peptide
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- Target See all APPL1 products
- APPL1 (Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 1 (APPL1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- DQPGQAKAFG QGGRRTNPFG ESGGSTKSET EDSILHQLFI VRFLGSMEVK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- APPL1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- APPL1 (Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 1 (APPL1))
- Synonyms
- APPL Peptide, DIP13alpha Peptide, 2900057D21Rik Peptide, 7330406P05Rik Peptide, AI585782 Peptide, AW209077 Peptide, BB022931 Peptide, C88264 Peptide, DIP13 Peptide, RGD1309388 Peptide, adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 Peptide, adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 Peptide, APPL1 Peptide, Appl1 Peptide
- Background
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The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.
Alias Symbols: APPL, DIP13alpha
Protein Size: 709 - Gene ID
- 26060
- NCBI Accession
- NM_012096, NP_036228
- UniProt
- Q9UKG1
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