Adaptor-Related Protein Complex 3, mu 1 Subunit (AP3M1) (C-Term) Peptide
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- Target See all AP3M1 products
- AP3M1 (Adaptor-Related Protein Complex 3, mu 1 Subunit (AP3M1))
- Protein Region
- C-Term
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- TQGSYTFDPV TKVLTWDVGK ITPQKLPSLK GLVNLQSGAP KPEENPSLNI
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-AP3M1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- AP3M1 (Adaptor-Related Protein Complex 3, mu 1 Subunit (AP3M1))
- Synonyms
- 1200013D09Rik Peptide, C78982 Peptide, R75378 Peptide, P47a Peptide, adaptor related protein complex 3 mu 1 subunit Peptide, adaptor-related protein complex 3, mu 1 subunit Peptide, AP3M1 Peptide, Ap3m1 Peptide
- Background
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The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane, and it may directly function in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternative splicing of this gene results in multiple transcript variants.
Protein Size: 418 - Gene ID
- 26985
- NCBI Accession
- NM_012095, NP_036227
- UniProt
- Q9Y2T2
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