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Natriuretic Peptide A (NPPA) (Middle Region) Peptide

NPPA Reactivity: Human Host: Synthetic WB, BP
Catalog No. ABIN5512752
  • Target See all NPPA products
    NPPA (Natriuretic Peptide A (NPPA))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 6
    Synthetic
    Application
    Western Blotting (WB), Blocking Peptide (BP)
    Sequence
    EVSPAQRDGG ALGRGPWDSS DRSALLKSKL RALLTAPRSL RRSSCFGGRM
    Characteristics
    This is a synthetic peptide designed for use in combination with anti- PRKACA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    NPPA (Natriuretic Peptide A (NPPA))
    Synonyms
    anp Peptide, ANF Peptide, ANP Peptide, Pnd Peptide, RATANF Peptide, ATFB6 Peptide, CDD-ANF Peptide, PND Peptide, NPPA Peptide, Anf Peptide, atrial natriuretic peptide Peptide, natriuretic peptide A Peptide, natriuretic peptide type A Peptide, anp Peptide, nppa Peptide, NPPA Peptide, Nppa Peptide
    Background
    The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. This gene is located adjacent to another member of the natriuretic family of peptides on chromosome 1.

    Alias Symbols: ANF, ANP, CDD, CDP, PND, ATFB6, ATRST2, CDD-ANF

    Protein Size: 153
    Gene ID
    4878
    NCBI Accession
    NM_006172, NP_006163
    UniProt
    P01160
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