Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L) (Middle Region) Peptide
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- Target See all ASH2L products
- ASH2L (Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- MTWPNNIVKT MSKERDVFLV KEHPDPGSKD PEEDYPKFGL LDQDLSNIGP
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ASH2L Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ASH2L (Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L))
- Synonyms
- ASH2 Peptide, ASH2L1 Peptide, ASH2L2 Peptide, Bre2 Peptide, fb34c06 Peptide, fe38b04 Peptide, fi20h02 Peptide, wu:fb34c06 Peptide, wu:fe38b04 Peptide, wu:fi20h02 Peptide, zgc:171444 Peptide, ASH2L Peptide, ash2-like Peptide, ASH2 like histone lysine methyltransferase complex subunit Peptide, ash2 (absent, small, or homeotic)-like (Drosophila) Peptide, ash2 (absent, small, or homeotic)-like L homeolog Peptide, ASH2L Peptide, Ash2l Peptide, ash2l Peptide, ash2l.L Peptide
- Background
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ASH2L is a component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. ASH2L may function as a transcriptional regulator and may play a role in hematopoiesis.
Alias Symbols: ASH2L,ASH2L1,
Protein Size: 628 - Gene ID
- 9070
- NCBI Accession
- NP_004665
- UniProt
- Q9UBL3
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