Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (Middle Region) Peptide
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- Target See all PIK3CA products
- PIK3CA (Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- IIVVIWVIVS PNNDKQKYTL KINHDCVPEQ VIAEAIRKKT RSMLLSSEQL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PIK3CA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PIK3CA (Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA))
- Synonyms
- CLOVE Peptide, CWS5 Peptide, MCAP Peptide, MCM Peptide, MCMTC Peptide, PI3K Peptide, p110-alpha Peptide, C-P3K Peptide, PI3-kinase Peptide, PI3K-alpha Peptide, pi3-k Peptide, pi3k Peptide, AA414921 Peptide, C530050K14 Peptide, p50alpha Peptide, p55alpha Peptide, p85alpha Peptide, 6330412C24Rik Peptide, caPI3K Peptide, p110 Peptide, p110alpha Peptide, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Peptide, Phosphoinositide-3-kinase, catalytic, alpha polypeptide Peptide, phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha Peptide, phosphoinositide-3-kinase regulatory subunit 1 Peptide, PIK3CA Peptide, GL50803_14855 Peptide, pik3ca Peptide, Pik3ca Peptide, Pik3r1 Peptide
- Background
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Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers.
Alias Symbols: MCM, CWS5, MCAP, PI3K, CLOVE, MCMTC, p110-alpha
Protein Size: 1608 - Gene ID
- 5290
- NCBI Accession
- NM_006218, NP_006209
- UniProt
- P42337
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