Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) (N-Term) Peptide
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- Target See all MAP2K6 products
- MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- MSQSKGKKRN PGLKIPKEAF EQPQTSSTPP RDLDSKACIS IGNQNFEVKA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- MAP2K6 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))
- Synonyms
- MAPKK6 Peptide, MEK6 Peptide, MKK6 Peptide, PRKMK6 Peptide, SAPKK-3 Peptide, SAPKK3 Peptide, Mkk6 Peptide, Prkmk6 Peptide, MKK3 Peptide, map2k3 Peptide, zMKK3 Peptide, map2k6 Peptide, mitogen-activated protein kinase kinase 6 Peptide, mitogen-activated protein kinase kinase 6 L homeolog Peptide, MAP2K6 Peptide, Map2k6 Peptide, map2k6 Peptide, map2k6.L Peptide
- Background
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This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.
Alias Symbols: MEK6, MKK6, MAPKK6, PRKMK6, SAPKK3, SAPKK-3
Protein Size: 334 - Gene ID
- 5608
- NCBI Accession
- NM_002758, NP_002749
- UniProt
- P52564
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