Interleukin-1 Receptor-Associated Kinase 3 (IRAK3) (Middle Region) Peptide
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- Target See all IRAK3 products
- IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- EDDESQNNNL LPSDEGLRID RMTQKTPFEC SQSEVMFLSL DKKPESKRNE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- IRAK3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))
- Synonyms
- IRAK3 Peptide, si:dkey-150i15.2 Peptide, ASRT5 Peptide, IRAKM Peptide, IrakM Peptide, 4833428C18Rik Peptide, AI563835 Peptide, IRAK-M Peptide, interleukin 1 receptor associated kinase 3 Peptide, interleukin-1 receptor-associated kinase 3 Peptide, IRAK3 Peptide, irak3 Peptide, Irak3 Peptide
- Background
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This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.
Alias Symbols: ASRT5, IRAKM
Protein Size: 596 - Gene ID
- 11213
- NCBI Accession
- NM_001142523, NP_001135995
- UniProt
- Q9Y616
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