Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15) (C-Term) Peptide
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- Target See all EPS15 products
- EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- KIGTPTRPCP LPPGKRSINK LDSPDPFKLN DPFQPFPGND SPKEKDPEIF
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- EPS15 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))
- Synonyms
- AF-1P Peptide, AF1P Peptide, MLLT5 Peptide, CG16932 Peptide, Dmel\\CG16932 Peptide, EH1 Peptide, EPS-15 Peptide, Eps15 Peptide, anon-WO0118547.85 Peptide, eps-15 Peptide, eps15 Peptide, i31 Peptide, 2410112D09Rik Peptide, RGD1307641 Peptide, epidermal growth factor receptor pathway substrate 15 Peptide, Epidermal growth factor receptor pathway substrate clone 15 Peptide, hypothetical protein Peptide, EPS15 Peptide, Eps-15 Peptide, eps15 Peptide, Eps15 Peptide, PGTG_06574 Peptide
- Background
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This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: AF1P, AF-1P, MLLT5
Protein Size: 582 - Gene ID
- 2060
- NCBI Accession
- NM_001159969, NP_001153441
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