Cold Inducible RNA Binding Protein (CIRBP) (Middle Region) Peptide
CIRBP
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CIRBP products
- CIRBP (Cold Inducible RNA Binding Protein (CIRBP))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SVDGRQIRVD QAGKSSDNRS RGYRGGSAGG RGFFRGGRGR GRGFSRGGGD
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CIRBP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CIRBP (Cold Inducible RNA Binding Protein (CIRBP))
- Background
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CIRBP is a cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. It acts as a translational activator. Seems to play an essential role in cold- induced suppression of cell proliferation. It binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. It acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.
Alias Symbols: CIRBP,A18HNRNP,CIRP,
Protein Size: 172 - Gene ID
- 1153
- NCBI Accession
- NP_001271
- UniProt
- Q14011
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