Diaphanous Homolog 1 (DIAPH1) (N-Term) Peptide
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- Target See all DIAPH1 products
- DIAPH1 (Diaphanous Homolog 1 (DIAPH1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PGGSLGPGRG TRDKKKGRSP DELPSAGGDG GKSKKFTLKR LMADELERFT
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- DIAPH1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DIAPH1 (Diaphanous Homolog 1 (DIAPH1))
- Synonyms
- DIAPH1 Peptide, dia1 Peptide, drf1 Peptide, dfna1 Peptide, diap1 Peptide, lfhl1 Peptide, DIAPH2 Peptide, Diap1 Peptide, D18Wsu154e Peptide, Dia1 Peptide, Diaph1 Peptide, Drf1 Peptide, mKIAA4062 Peptide, p140mDia Peptide, DFNA1 Peptide, DIA1 Peptide, DRF1 Peptide, LFHL1 Peptide, hDIA1 Peptide, diaphanous related formin 1 Peptide, diaphanous related formin 2 Peptide, diaphanous-related formin 1 Peptide, protein diaphanous homolog 1 Peptide, DIAPH1 Peptide, diaph1 Peptide, DIAPH2 Peptide, Diaph1 Peptide, LOC100457442 Peptide
- Background
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This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: DIA1, DRF1, DFNA1, LFHL1, SCBMS, hDIA1
Protein Size: 1272 - Gene ID
- 1729
- NCBI Accession
- NM_001079812, NP_001073280
- UniProt
- O60610
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