Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) (N-Term) Peptide
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- Target See all TRPV5 products
- TRPV5 (Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- GFLPKAEGPG SQLQKLLPSF LVREQDWDQH LDKLHMLQQK RILESPLLRA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TRPV5 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TRPV5 (Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5))
- Synonyms
- CaT2 Peptide, Ecac1 Peptide, CAT2 Peptide, ECAC1 Peptide, OTRPC3 Peptide, D630033B11 Peptide, TRPV5 Peptide, ECAC Peptide, cat2 Peptide, xcat2 Peptide, transient receptor potential cation channel, subfamily V, member 5 Peptide, transient receptor potential cation channel subfamily V member 5 Peptide, calcium transporter 2 L homeolog Peptide, Trpv5 Peptide, TRPV5 Peptide, LOC100011049 Peptide, trpv5 Peptide, cat2.L Peptide
- Background
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TRPV5 constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine. The channel is activated by low internal calcium level and the current exhibits an inward rectification. A Ca(2+)- dependent feedback regulation includes fast channel inactivation and slow current decay. Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.
Alias Symbols: TRPV5,ECAC1,
Protein Size: 729 - Gene ID
- 56302
- NCBI Accession
- NP_062815
- UniProt
- Q9NQA5
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