PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1) (Middle Region) Peptide
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- Target See all PMS1 products
- PMS1 (PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PFQNDMHNDE SGKNTDDCLN HQISIGDFGY GHCSSEISNI DKNTKNAFQD
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- PMS1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PMS1 (PMS1 Postmeiotic Segregation Increased 1 (S. Cerevisiae) (PMS1))
- Synonyms
- PMSL1 Peptide, si:dz72b14.2 Peptide, si:dz164h20.2 Peptide, PMS1 Peptide, DKFZp468M105 Peptide, pms1 Peptide, HNPCC3 Peptide, hPMS1 Peptide, PMS1 homolog 1, mismatch repair system component Peptide, PMS1 homolog 1, mismatch repair system component S homeolog Peptide, PMS1 Peptide, Pms1 Peptide, pms1 Peptide, pms1.S Peptide
- Background
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This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.
Alias Symbols: MLH2, PMSL1, hPMS1, HNPCC3
Protein Size: 932 - Gene ID
- 5378
- NCBI Accession
- NM_000534, NP_000525
- UniProt
- P54277
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