Paired Box 3 (PAX3) (C-Term) Peptide
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- Target See all Paired Box 3 (PAX3) products
- Paired Box 3 (PAX3)
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SSAYCLPSTR HGFSSYTDSF VPPSGPSNPM NPTIGNGLSP QVPFIISSQI
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PAX3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Paired Box 3 (PAX3)
- Synonyms
- PAX3 Peptide, cdhs Peptide, hup2 Peptide, pax-3 Peptide, ws1 Peptide, xpax3 Peptide, Pax3 Peptide, pax3 Peptide, pax3b Peptide, xPax3-B Peptide, CDHS Peptide, HUP2 Peptide, WS1 Peptide, WS3 Peptide, Pax-3 Peptide, Sp Peptide, splotch Peptide, zgc:92547 Peptide, paired box 3 Peptide, paired box 3 L homeolog Peptide, paired box 3a Peptide, PAX3 Peptide, pax3 Peptide, pax3.L Peptide, Pax3 Peptide, pax3a Peptide
- Background
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This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.
Alias Symbols: PAX3,HUP2,
Protein Size: 403 - Gene ID
- 5077
- NCBI Accession
- NP_852126
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