Major Vault Protein (MVP) (Middle Region) Peptide
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- Target See all MVP products
- MVP (Major Vault Protein (MVP))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- ELLNKGQDPL ADRGEKDTAK SLQPLAPRNK TRVVSYRVPH NAAVQVYDYR
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MVP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MVP (Major Vault Protein (MVP))
- Background
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This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.
Alias Symbols: MVP,LRP,
Protein Size: 893 - Gene ID
- 9961
- NCBI Accession
- NP_059447
- UniProt
- Q14764
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