Myeloid Differentiation Primary Response Gene (88) (MYD88) (Middle Region) Peptide
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- Target See all MYD88 products
- MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- NVRTQVAADW TALAEEMDFE YLEIRQLETQ ADPTGRLLDA WQGRPGASVG
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MYD88 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))
- Synonyms
- MYD88D Peptide, XMyD88 Peptide, myd88d Peptide, MGC84928 Peptide, CG2078 Peptide, DMMYD88 Peptide, DmMyD88 Peptide, DmMyd88 Peptide, Dmel\\CG2078 Peptide, EP(2)2535 Peptide, Kra Peptide, LD20892 Peptide, MYD88 Peptide, MyD88 Peptide, Myd88F Peptide, dMyD88 Peptide, dMyd88 Peptide, kra Peptide, myd88 Peptide, zgc:103541 Peptide, GB12344 Peptide, NV10640 Peptide, myd88-a Peptide, myd88-b Peptide, myeloid differentiation primary response 88 Peptide, myeloid differentiation primary response 88 S homeolog Peptide, myeloid differentiation primary response gene 88 Peptide, CG2078 gene product from transcript CG2078-RB Peptide, myeloid differentiation primary response protein MyD88-A Peptide, myeloid differentiation primary response protein MyD88 Peptide, myeloid differentiation factor 88 Peptide, myeloid differentiation primary response 88 L homeolog Peptide, MYD88 Peptide, myd88.S Peptide, Myd88 Peptide, myd88 Peptide, LOC413194 Peptide, LOC100118553 Peptide, LOC575153 Peptide, myd88.L Peptide
- Background
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This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
Alias Symbols: MYD88D
Protein Size: 296 - Gene ID
- 4615
- NCBI Accession
- NM_001172566, NP_001166037
- UniProt
- Q99836
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