Ribosomal Protein S19 (RPS19) (C-Term) Peptide
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- Target See all RPS19 products
- RPS19 (Ribosomal Protein S19 (RPS19))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SKSVARRVLQ ALEGLKMVEK DQDGGRKLTP QGQRDLDRIA GQVAAANKKH
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RS19 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RPS19 (Ribosomal Protein S19 (RPS19))
- Synonyms
- DBA Peptide, DBA1 Peptide, S19 Peptide, Dsk3 Peptide, 30S ribosomal protein S19 Peptide, 40S ribosomal protein S19 Peptide, ribosomal protein S19 Peptide, rps19 Peptide, rps-19 Peptide, RPS19 Peptide, Rps19 Peptide
- Background
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Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Alias Symbols: RPS19,
Protein Size: 145 - Gene ID
- 6223
- NCBI Accession
- NP_001013
- UniProt
- P39019
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