Phospholipase C gamma 2 (PLCG2) (Middle Region) Peptide
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- Target See all Phospholipase C gamma 2 (PLCG2) products
- Phospholipase C gamma 2 (PLCG2)
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- ETHLRCAEFE LRLTDPVPNP NPHESKPWYY DSLSRGEAED MLMRIPRDGA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PLCG2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Phospholipase C gamma 2 (PLCG2)
- Synonyms
- PLCgamma2 Peptide, Plcg-2 Peptide, APLAID Peptide, FCAS3 Peptide, phospholipase C, gamma 2 Peptide, phospholipase C gamma 2 Peptide, phospholipase C, gamma 2 (phosphatidylinositol-specific) Peptide, Plcg2 Peptide, PLCG2 Peptide
- Background
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The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane.
Alias Symbols: PLCG2,
Protein Size: 1265 - Gene ID
- 5336
- NCBI Accession
- NM_002661, NP_002652
- UniProt
- P16885
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