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Sirtuin 3 (SIRT3) (N-Term) Peptide

SIRT3 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5511098
  • Target See all SIRT3 products
    SIRT3 (Sirtuin 3 (SIRT3))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 8
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    AAAPSFFFSS IKGGRRSISF SVGASSVVGS GGSSDKGKLS LQDVAELIRA
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-SIR3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    SIRT3 (Sirtuin 3 (SIRT3))
    Synonyms
    zgc:158774 Peptide, sirtuin Peptide, SIR2L3 Peptide, 2310003L23Rik Peptide, AI848213 Peptide, Sir2l3 Peptide, sirtuin 3 Peptide, sirt3 Peptide, SIRT3 Peptide, Sirt3 Peptide
    Background
    This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.

    Alias Symbols: SIRT3,SIR2L3,

    Protein Size: 399
    Gene ID
    23410
    NCBI Accession
    NP_036371
    UniProt
    Q9NTG7
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