Integrin alpha-L (ITGAL) (Middle Region) Peptide
ITGAL
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ITGAL products
- ITGAL (Integrin alpha-L (ITGAL))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- MSCTDFSFHF PVCVQDLISP INVSLNFSLW EEEGTPRDQR AQGKDIPPIL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ITGAL Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ITGAL (Integrin alpha-L (ITGAL))
- Background
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ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CD11A, LFA-1, LFA1A
Protein Size: 1170 - Gene ID
- 3683
- NCBI Accession
- NM_001114380, NP_001107852
- UniProt
- P20701
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