Caspase Recruitment Domain Family, Member 11 (CARD11) (Middle Region) Peptide
CARD11
Reactivity: Human
Host: Synthetic
BP, WB
-
- Target See all CARD11 products
- CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
- Protein Region
- Middle Region
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SPRLSRASFL FGQLLQFVSR SENKYKRMNS NERVRIISGS PLGSLARSSL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CARD11 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Caspase Recruitment Domain Family, Member 11 (CARD11) peptide
CARD11 Reactivity: Human, Mouse, Cow, Dog Host: Synthetic BP, Imm
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
- Background
-
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.
Alias Symbols: PPBL, BENTA, BIMP3, IMD11, CARMA1
Protein Size: 1171 - Gene ID
- 84433
- NCBI Accession
- NM_032415, NP_115791
- UniProt
- Q8TES3
-
You are here:
