Activating Transcription Factor 2 (ATF2) (C-Term) Peptide
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- Target See all ATF2 products
- ATF2 (Activating Transcription Factor 2 (ATF2))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PVTAMQKKSG YHTADKDDSS EDISVPSSPH TEAIQHSSVS TSNGVSSTSK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ATF2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ATF2 (Activating Transcription Factor 2 (ATF2))
- Synonyms
- CRE-BP1 Peptide, CREB2 Peptide, HB16 Peptide, TREB7 Peptide, CG12850 Peptide, CG3749 Peptide, dATF-2 Peptide, DmelCG30420 Peptide, CG30420 Peptide, CHN1 Peptide, Atf-2 Peptide, CRE-BP Peptide, Creb2 Peptide, D130078H02Rik Peptide, D18875 Peptide, Tg(Gzma-Klra1)7Wum Peptide, mXBP Peptide, atf2-A Peptide, atf2l Peptide, activating transcription factor 2 Peptide, Activating transcription factor-2 Peptide, activating transcription factor 2 S homeolog Peptide, ATF2 Peptide, Atf-2 Peptide, Atf2 Peptide, atf2.S Peptide, atf2 Peptide
- Background
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This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene.
Alias Symbols: ATF2,CREB2, CREBP1,
Protein Size: 487 - Gene ID
- 1386
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