Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (C-Term) Peptide
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- Target See all eIF4EBP1 (EIF4EBP1) products
- eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- NSPVTKTPPR DLPTIPGVTS PSSDEPPMEA SQSHLRNSPE DKRAGGEESQ
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-4EBP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
- Synonyms
- 4E-BP1 Peptide, 4EBP1 Peptide, BP-1 Peptide, PHAS-I Peptide, 4e-bp1 Peptide, AA959816 Peptide, 153432_at Peptide, 43-BP Peptide, 4E-BP Peptide, 4EBP Peptide, 4e-bp Peptide, 4eBP Peptide, 4ebp Peptide, BcDNA.HL08053 Peptide, BcDNA:HL08053 Peptide, CG8846 Peptide, CT8705 Peptide, Dm 4E-BP Peptide, Dmel\\CG8846 Peptide, Phas1 Peptide, Thor/EIF4EBP Peptide, anon-WO0172774.158 Peptide, d4E-BP Peptide, d4E-BP1 Peptide, d4EBP Peptide, d4e-bp Peptide, d4eBP Peptide, dthor Peptide, eIF4E-BP Peptide, l(2)06270 Peptide, l(2)k07736 Peptide, l(2)k13517 Peptide, pp20 Peptide, thor Peptide, EIF4EBP1 Peptide, fc04h09 Peptide, wu:fc04h09 Peptide, zgc:64137 Peptide, eukaryotic translation initiation factor 4E binding protein 1 Peptide, CG8846 gene product from transcript CG8846-RA Peptide, EIF4EBP1 Peptide, Eif4ebp1 Peptide, Thor Peptide, eif4ebp1 Peptide
- Background
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This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Alias Symbols: EIF4EBP1,
Protein Size: 118 - Gene ID
- 1978
- NCBI Accession
- NP_004086
- UniProt
- Q13541
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