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PDZ and LIM Domain 2 (PDLIM2) (N-Term) Peptide

PDLIM2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5510835
  • Target See all PDLIM2 products
    PDLIM2 (PDZ and LIM Domain 2 (PDLIM2))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    LHAEAQSKIR QSPSPLRLQL DRSQATSPGQ TNGDSSLEVL ATRFQGSVRT
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-PDLI2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PDLIM2 (PDZ and LIM Domain 2 (PDLIM2))
    Background
    This gene encodes a member of the ALP subfamily of PDZ-LIM domain proteins. The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain. The encoded protein is also a putative tumor suppressor protein, and decreased expression of this gene is associated with several malignancies including breast cancer and adult T-cell leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

    Alias Symbols: PDLIM2,PP6345,

    Protein Size: 352
    Gene ID
    64236
    UniProt
    Q96JY6
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