Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT) (Ile8) Peptide
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- Target See all AGT products
- AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))
- Protein Region
- Ile8
- Purity
- > 95 %
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- Restrictions
- For Research Use only
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- Storage
- -20 °C
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- Target
- AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))
- Synonyms
- ANHU Peptide, SERPINA8 Peptide, AI265500 Peptide, AngI Peptide, AngII Peptide, Aogen Peptide, Serpina8 Peptide, ANRT Peptide, Ang Peptide, PAT Peptide, wu:fb62f06 Peptide, wu:fj87b02 Peptide, zgc:111892 Peptide, AGT Peptide, angt Peptide, ANGT Peptide, angiotensinogen Peptide, angiotensinogen (serpin peptidase inhibitor, clade A, member 8) Peptide, AGT Peptide, Agt Peptide, agt Peptide
- Background
- The biological activities of angiotensin II antagonists upon basal and angiotensin II-stimulated aldosterone production were evaluated in an isolated canine glomerulosa cell preparation. Our investigations found that the most potent competitive antagonist of angiotensin II-stimulated aldosterone production was the [Sar1, Ile8] derivative of angiotensin II. However, this peptide was also a partial agonist at concentrations required to inhibit the steroidogenic effect of angiotensin II on dog adrenal cells, and never reduced aldosterone production to basal levels.
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