Substance P (AA 1-9) Peptide
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- Target See all Substance P products
- Substance P
- Protein Region
- AA 1-9
- Purity
- > 95 %
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- Restrictions
- For Research Use only
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- Storage
- -20 °C
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- Target
- Substance P
- Synonyms
- Hs.2563 Peptide, NK2 Peptide, NKNA Peptide, NPK Peptide, TAC2 Peptide, PPTA3 Peptide, Ppt5fl Peptide, RATPPTA3 Peptide, TAC Peptide, 4930528L02Rik Peptide, NK-1 Peptide, NK1 Peptide, Nkna Peptide, PPT-A Peptide, PPTA Peptide, SP Peptide, PPT Peptide, beta-PPT-A Peptide, NKA Peptide, tachykinin precursor 1 Peptide, tachykinin, precursor 1 Peptide, tachykinin 1 Peptide, TAC1 Peptide, Tac1 Peptide
- Background
- Subtance P is responsible for a number of excitatory effects on both central and peripheral neurons. Substance P contracts smooth muscle, constricts bronchioles and increases capillary permeability. When released from afferent nerves, Substance P causes a neurogenic inflammatory response, including mast cell degranulation. NK-1 agonist, potent vasodilator and hypotensive agent, induces salivation, putative neurotransmitter in sensory (pain) afferents. Substance P(1-9) is a fragment of Subtance P. Accumulating evidence shows that N- and C-terminal substance P fragments have significant biological activity. Substance P(1-9) has been reported to be major substance P metabolites in rat striatum and it has modulatory effects similar to substance P.
- CAS-No
- 57468-17-4
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