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- Target See all Substance P products
- Substance P
- Purity
- > 95 %
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- Restrictions
- For Research Use only
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- Storage
- -20 °C
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Effects of cations on protein and peptide charging in electrospray ionization from aqueous solutions." in: Journal of the American Society for Mass Spectrometry, Vol. 25, Issue 6, pp. 918-27, (2014) (PubMed).
: "On-line large-volume electroextraction coupled to liquid chromatography-mass spectrometry to improve detection of peptides." in: Journal of chromatography. A, Vol. 1249, pp. 17-24, (2012) (PubMed).
: "Online capillary liquid-liquid electroextraction of peptides as fast pre-concentration prior to LC-MS." in: Electrophoresis, Vol. 31, Issue 23-24, pp. 3903-12, (2010) (PubMed).
: "Investigation of the pruritogenic effects of histamine, serotonin, tryptase, substance P and interleukin-2 in healthy dogs." in: Veterinary dermatology, Vol. 20, Issue 2, pp. 105-10, (2009) (PubMed).
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Effects of cations on protein and peptide charging in electrospray ionization from aqueous solutions." in: Journal of the American Society for Mass Spectrometry, Vol. 25, Issue 6, pp. 918-27, (2014) (PubMed).
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- Target
- Substance P
- Synonyms
- Hs.2563 Peptide, NK2 Peptide, NKNA Peptide, NPK Peptide, TAC2 Peptide, PPTA3 Peptide, Ppt5fl Peptide, RATPPTA3 Peptide, TAC Peptide, 4930528L02Rik Peptide, NK-1 Peptide, NK1 Peptide, Nkna Peptide, PPT-A Peptide, PPTA Peptide, SP Peptide, PPT Peptide, beta-PPT-A Peptide, NKA Peptide, tachykinin precursor 1 Peptide, tachykinin, precursor 1 Peptide, tachykinin 1 Peptide, TAC1 Peptide, Tac1 Peptide
- Background
- Substance P is found in the gut and in the brain. It is responsible for a number of excitatory effects on both central and peripheral neurons. Substance P contracts smooth muscle, constricts bronchioles, and increases capillary permeability. When released from afferent nerves, Substance P causes a neurogenic inflammatory response, including mast cell degranulation. It's an NK-1 agonist, a potent vasodilator and hypotensive agent, it induces salivation, it's a putative neurotransmitter in sensory (pain) afferents.
- CAS-No
- 33507-63-0
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