F-Box and WD Repeat Domain Containing 7 (FBXW7) Peptide
FBXW7
Reactivity: Human
Host: Rabbit
BP
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- Target See all FBXW7 products
- FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
- Origin
- Human
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Source
- Rabbit
- Application
- Blocking Peptide (BP)
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- Restrictions
- For Research Use only
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- Storage
- -80 °C
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- Target
- FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
- Background
- Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Involved in the degradation of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1.
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