Paired Box 8 (PAX8) (C-Term) Peptide
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- Target See all PAX8 products
- PAX8 (Paired Box 8 (PAX8))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- TPSNTPLGRN LSTHQTYPVV ADPHSPFAIK QETPEVSSSS STPSSLSSSA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PAX8 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PAX8 (Paired Box 8 (PAX8))
- Synonyms
- PAX8 Peptide, XPax-8 Peptide, XPax8 Peptide, pax-8 Peptide, PAX-8 Peptide, Pax-8 Peptide, paired box 8 Peptide, paired box 8 L homeolog Peptide, PAX8 Peptide, pax8 Peptide, Pax8 Peptide, pax8.L Peptide
- Background
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PAX8 is a member of the paired box (PAX) family of transcription factors. Members of this family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in its gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas.
Alias Symbols: -
Protein Size: 450 - Molecular Weight
- 48 kDa
- Gene ID
- 7849
- NCBI Accession
- NM_013992, NP_054698
- UniProt
- Q06710
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