SARS-CoV-2 Envelope (SARS-CoV-2 E) (N-Term) Peptide
SARS-CoV-2 E
Reactivity: SARS Coronavirus (SARS-CoV), SARS Coronavirus-2 (SARS-CoV-2)
BP
Sodium azide
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- Target See all SARS-CoV-2 Envelope (SARS-CoV-2 E) products
- SARS-CoV-2 Envelope (SARS-CoV-2 E)
- Protein Region
- N-Term
- Origin
- SARS Coronavirus (SARS-CoV), SARS Coronavirus-2 (SARS-CoV-2)
- Application
- Blocking Peptide (BP)
- Characteristics
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10 amino acids near the amino terminus of SARS E protein.
Virus
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- Application Notes
- SARS envelope peptide is used for blocking the activity of the SARS envelope.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 200 μg/mL
- Buffer
- PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- SARS-CoV-2 Envelope (SARS-CoV-2 E)
- Synonyms
- envelope protein Peptide, E Peptide
- Target Type
- Viral Protein
- Background
- Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus. The disease is the cause of the 2019–20 coronavirus outbreak. The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. Envelope protein is a small polypeptide that contains at least one α-helical transmembrane domain. It involves in several aspects of the virus's life cycle, such as assembly, budding, envelope formation, and pathogenesis. E protein has membrane permeabilizing activity, which provides a possible rationale to inhibit in vitro ion channel activity of some synthetic coronavirus E proteins, and also viral replication.
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